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检测感染HBV的饮食服务人群的HBVDNA ,研究HBVDNA阳性者的家庭聚集性 ,探讨其传染性 ,为修订有关法规提供依据。用聚合酶联反应 -微孔杂交法和荧光定量PCR法检测HBVDNA ,对HBVDNA阳性者的家庭聚集性进行对照研究。在 2 85 16名饮食服务人员中检出HBsAg阳性 10 2 2人 ,阳性率 3 5 8%。其中被依法调离的HBV感染者 36 4人 ,占HBsAg阳性者的 35 6 2 %。在感染HBV且符合法律规定的 6 5 8名在岗饮食服务人员中检出HBVDNA阳性者 2 34人 ,阳性率35 5 6 %。HBVDNA阳性者的家庭聚集率为 86 4 9% ,家庭成员HBV感染率为 6 4 38% ,相对危险性6 5 8。HBVDNA阳性者的家庭成员HBV感染呈家庭聚集性。研究结果表明HBVDNA阳性的在岗饮食服务人员血清学检验结果符合法律规定 ,但是HBV的危险传染源。
To detect HBVDNA in HBV-infected diet service population, to study the family aggregation of HBVDNA positive persons and to explore their contagiousness, so as to provide basis for the revision of relevant laws and regulations. HBVDNA was detected by polymerase chain reaction-microplate hybridization and fluorescence quantitative PCR, and the family aggregation of HBVDNA-positive patients were compared. Of the 2 85 16 food service workers, 102 2 were positive for HBsAg, with a positive rate of 35.8%. Among them, 364 were HBV infected persons who were transferred according to law, accounting for 35 6 2% of those with HBsAg positive. Among the 558 on-the-job food service workers infected with HBV and in compliance with the law, 2 34 were HBVDNA positive, with a positive rate of 35 5 6%. The incidence of familial HBV infection was 86.49% in HBVDNA-positive patients and 6 4 38% in HBV-infected relatives. The relative risk of HBV infection was 65.8%. HBV infection in family members with HBVDNA positive was family clustering. The results showed that HBVDNA positive in-service dietitian serological test results in line with the law, but the source of dangerous HBV infection.