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呼吸机相关肺炎(VAP)是指机械通气48小时后出现的肺实质感染,是机械通气患者常见的并发症和死亡原因。国外报道,VAP发生率为9% ̄70%,病死率达50% ̄69%[1]国内有医院调查,VAP发生率为43.1%[2]不同医院中VAP的病死率为24% ̄76%[3]VAP一旦发生,常常造成机械通气患者撤机困难,不但延长患者住院时间,增加住院费用,严重者甚至导致机械通气失败,威胁病人生命。
Ventilator-associated pneumonia (VAP) refers to pulmonary parenchymal infection that occurs 48 hours after mechanical ventilation and is a common complication and cause of death in patients with mechanical ventilation. Foreign reports, VAP incidence of 9% ~ 70%, mortality rate of 50% ~ 69% [1] domestic hospital survey, the incidence of VAP was 43.1% [2] VAC in different hospitals, the mortality rate was 24% ~ 76 % [3] In the event of VAP, it often results in difficulty in weaning patients with mechanical ventilation, which not only prolongs hospitalization time and increases hospitalization costs, but also results in failure of mechanical ventilation and threat to patient’s life.