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目的观察多烯磷脂酰胆碱辅治酒精性肝炎与脂肪肝的临床效果。方法选取酒精性肝炎与脂肪肝患者76例。随机分为观察组与对照组各38例。2组均接受常规治疗,观察组在此基础上辅以多烯磷脂酰胆碱治疗。观察2组治疗效果及各项肝功能指标变化情况。结果观察组总有效率为94.7%,高于对照组的68.4%(χ2=6.48,P<0.05);治疗后2组肝功能各项指标均显著降低,观察组降低幅度显著大于对照组且观察组各项指标均明显低于对照组(P<0.05)。结论多烯磷脂酰胆碱辅治酒精性肝炎与脂肪肝,疗效确切,可有效缓解患者症状,促进患者康复,值得临床推广应用。
Objective To observe the clinical effect of polyene phosphatidylcholine in treating alcoholic hepatitis and fatty liver. Methods 76 patients with alcoholic hepatitis and fatty liver were selected. Randomly divided into observation group and control group, 38 cases each. Both groups received routine treatment, and the observation group was supplemented with polyene phosphatidylcholine. The effect of treatment and the changes of liver function indexes were observed. Results The total effective rate in the observation group was 94.7%, higher than that in the control group (χ2 = 6.48, P <0.05). After treatment, the indexes of liver function in the two groups were significantly decreased, and the decrease in the observation group was significantly greater than that in the control group Group indicators were significantly lower than the control group (P <0.05). Conclusion Polyene phosphatidylcholine treatment of alcoholic hepatitis and fatty liver, the exact effect, which can effectively alleviate the symptoms and promote patient rehabilitation, is worthy of clinical application.