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目的了解上海市浦东新区流感样病例病毒谱特征,为科学有效的防控措施提供依据。方法 2013—2015年采集7家医疗机构流感样病例标本,进行人流感病毒、人腺病毒、鼻病毒、人副流感病毒、呼吸道合胞病毒、人冠状病毒、人偏肺病毒和人博卡病毒检测。结果 3年共2 131例流感样病例纳入监测,年龄中位数33岁;任一病毒阳性率为35.19%(750/2 131),其中单一病毒感染占90.80%(681/750),混合感染占9.20%(69/750)。单一病毒感染中,人流感病毒阳性率最高(17.55%,374/2 131),以A(H3N2)型(53.74%,201/374)为主;其次是鼻病毒(4.36%,93/2131)。任一病毒阳性率高峰在2014年1月(68.89%,31/45)和2015年1月(57.26%,71/124)。人流感病毒在冬季(12~2月)和夏季(7~9月)为优势病毒,鼻病毒在春季(3~6月)和秋季(10~11月)为优势病毒。结论监测期间人流感病毒为该区流感样病例的优势病毒,全年呈现冬季和夏季2个流行高峰。除了人流感病毒,流感样病例也由其他呼吸道病毒引起,尤其在流感非流行季节。
Objective To understand the virus spectrum characteristics of influenza-like illness in Pudong New Area, Shanghai, and to provide a basis for scientific and effective prevention and control measures. Methods From 2013 to 2015, seven samples of influenza-like illness were collected from medical institutions for human influenza virus, human adenovirus, rhinovirus, human parainfluenza virus, respiratory syncytial virus, human coronavirus, human metapneumovirus and human Boka virus Detection. Results A total of 2 131 influenza-like cases were enrolled in the study over the 3 years. The median age was 33 years. The positive rate of any one virus was 35.19% (750/2 131), of which 90.80% (681/750) Accounting for 9.20% (69/750). The positive rate of human influenza virus was the highest (17.55%, 374/2 131) in the single virus infection, which was mainly A (H3N2) (53.74%, 201/374), followed by rhinovirus (4.36%, 93/2131) . The positive rates of any one virus in January 2014 (68.89%, 31/45) and January 2015 (57.26%, 71/124). Human influenza virus is the predominant virus in winter (from July to February) and in summer (from July to September). Rhinovirus is dominant virus in spring (March to June) and autumn (from October to November). Conclusions During the monitoring period, the human influenza virus is the predominant virus of influenza-like cases in this area. There are two epidemic peaks in winter and summer throughout the year. In addition to human influenza viruses, flu-like cases are also caused by other respiratory viruses, especially during the non-flu season.