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目的:探讨肝病患者脂蛋白和载脂蛋白水平与疾病的关系。方法:测定89例肝病患者(包括慢性乙型肝炎47例、肝硬化患者36例、肝癌患者29例)和84例正常人血清HDL、LDL、载脂蛋白apoA 1、apoB和apoA 5水平。结果:肝病患者血清的上述血脂水平与正常对照组比较都有不同程度的下降,降低的程度以肝硬化组>肝癌组>慢性乙肝组。结论:肝病患者血清脂蛋白和载脂蛋白水平的降低可以反映肝脏功能的损伤程度。
Objective: To investigate the relationship between the levels of lipoprotein and apolipoprotein in patients with liver diseases and diseases. Methods: The serum levels of HDL, LDL, apolipoprotein a, apolipoprotein A, apoB and apoA 5 in 89 patients with liver disease (including 47 with chronic hepatitis B, 36 with cirrhosis and 29 with liver cancer) and 84 normal controls were measured. Results: The levels of serum lipids in patients with liver disease had decreased to some extent compared with the control group, and the degree of decrease was in cirrhosis group> HCC group> chronic hepatitis B group. Conclusion: The decrease of serum lipoprotein and apolipoprotein in patients with liver diseases can reflect the damage degree of liver function.