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目的:中药配合肝动脉栓塞化疗术(介入)治疗肝癌,观察中药对肝癌介入治疗后肝储备功能损伤的临床效果。方法:将63例中晚期肝癌患者随机分成试验组(31例)和对照组(32例),两组在介入治疗后均予西药常规护肝治疗,试验组在介入后加服健脾补气为主中药。两组分别在第1、第2次介入前和第2次介入后30d各检查吲哚靛青绿15 min潴留率(ICGR_(15)),观察两组患者ICGR_(15)在介入治疗前后的变化。结果:第1次介入治疗前IC-GR_(15):试验组(11.15±7.21)％,对照组(11.58±7. 13)％(P>0.05);第2次介入治疗前ICGR_(15):试验组(12.30±5.35)％,对照组(18.16±9.96)％(P<0.05);第2次介入治疗后30d ICGR_(15):试验组为(13.14±5.60)％,对照组(19.58±10.63)％(P<0.05)。结论:健脾补气中药能防治肝癌介入治疗后所引起的肝储备功能的损害。
Objective: Chinese medicine combined with hepatic artery chemoembolization (intervention) for the treatment of liver cancer, observe the clinical effect of traditional Chinese medicine on liver function impairment after interventional treatment of liver cancer. Methods: Sixty-three patients with advanced hepatocellular carcinoma (HCC) were randomly divided into experimental group (31 cases) and control group (32 cases). Both groups received conventional hepatoprotective therapy after interventional therapy. After the intervention, Main Chinese medicine. The retention rate of indocyanine green 15 min (ICGR_ (15)) before and after the second intervention was examined in both groups before and after the intervention, and the changes of ICGR_ (15) in both groups before and after the intervention were observed . Results: Before the first intervention, the ICGR_ (15) in the experimental group (11.15 ± 7.21)% and the control group (11.58 ± 7.13)% (P> 0.05) (13.14 ± 5.60)% in the experimental group and control group (19.58%) in the experimental group (12.30 ± 5.35)% and 18.16 ± 9.96% (P <0.05) ± 10.63)% (P <0.05). Conclusion: Chinese herbal medicine for invigorating spleen and qi can prevent the damage of liver reserve caused by interventional therapy of liver cancer.