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[目的]探讨癫痫患者抑郁障碍与负性生活事件的关系。[方法]抑郁障碍诊断采用中国神经精神障碍分类与诊断标准第3版(CCMD-3)单相抑郁发病的诊断标准。对58名癫痫患者按是否受负性生活事件影响分为负性生活事件影响组(n=30)、非负性生活事件影响组(n=28),对两组进行比较分析。[结果]负性生活事件影响组、非负性生活事件影响组抑郁的发生率分别为73.3%、17.9%,两者比较差异有统计学意义(χ2=15.76,P﹤0.001);负性生活事件刺激量与抑郁障碍呈正相关。[结论]癫痫患者并发抑郁障碍与负性生活事件相关。
[Objective] To investigate the relationship between depression and negative life events in patients with epilepsy. [Methods] Depression diagnosis was diagnosed by using the diagnostic criteria of monophasic depression in Chinese Classification and Diagnostic Criteria of Neuropsychiatric Disorders, 3rd edition (CCMD-3). Fifty-eight patients with epilepsy were divided into two groups according to whether they were affected by negative life events: negative life events (n = 30) and non-negative life events (n = 28). [Results] The incidence of depression in the group of negative life events and non-negative life events were 73.3% and 17.9%, respectively (χ2 = 15.76, P <0.001). Negative life The amount of incident stimuli was positively correlated with depression. [Conclusions] Concurrent depression is associated with negative life events in patients with epilepsy.