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目的:探讨人髓样相关蛋白14(Myeloid-Related Protein-14,MRP14)诱导THP-1细胞表达干扰素诱导蛋白-10(Interferong Inducible Protein,IP-10)的信号机制。方法:Liqui Chip液相蛋白芯片系统检测MRP14诱导THP-1细胞IP-10表达上调的时间及浓度依赖关系、MRP14不同结构域刺激THP-1?
AIM: To investigate the signaling pathway of Myeloid-Related Protein-14 (MRP14) -induced Interferong Inducible Protein-10 (THP-1) expression in THP-1 cells. Methods: Liqui Chip liquid phase protein chip system was used to detect the up-regulation of IP-10 expression in THP-1 cells induced by MRP14 and the concentration dependent manner. Different domains of MRP14 stimulated THP-1?