【摘 要】
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The microstructure, mechanical property, electrochemical behavior and biocompatibility of magnesium alloy (BioDe MSM?) were studied in the present work. The exp
【机 构】
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Center for Biomedical Materials and Engineering
论文部分内容阅读
The microstructure, mechanical property, electrochemical behavior and biocompatibility of magnesium alloy (BioDe MSM?) were studied in the present work. The experimental results demonstrated that grain refining induced by extrusion improves the alloy strength significantly from 162 MPa for the as-cast alloy to 241 MPa for the as-extruded one. The anticorrosion properties of the as-extruded alloy also increased. Furthermore, the hemolysis ratio was decreased from 4.7%for the as-cast alloy to 2.9%for the as-extruded one, both below 5%. BioDe MSM?alloy shows good biocompatibility after being implanted into the dorsal muscle and the femoral shaft of the New Zealand rabbit, respectively, and there are no abnormalities after short-term implantation. In vivo observation indicated that the corrosion rate of this alloy varies with different implantation positions, with higher degradation rate in the femur than in the muscle.
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