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目的:研究影响口腔鳞状细胞癌(Oral squamous cellcar cinoma,OSCC)术后患者预后的临床病理因素。方法:回顾性研究55例手术治疗的原发口腔鳞状细胞癌患者与预后相关的因素:年龄、性别、发病部位、颈部淋巴结转移情况、肿瘤细胞分化程度等。结果:平均发病年龄为57.35±12.02岁,牙龈鳞癌的复发转移率最高(45.5%),舌部第二(44%),颊部第三(37.5%),唇癌预后最好(0.0%)。术前颈部淋巴结转移情况、肿瘤细胞分化程度与预后有关。肿瘤细胞的分化程度与术前淋巴结转移无显著相关性。术前有颈部淋巴结转移合并中低分化与预后差相关。结论:口腔鳞状细胞癌的预后与发病部位无显著相关性。肿瘤中低分化及术前有淋巴结转移者易出现术后复发转移。
Objective: To investigate the clinicopathological factors affecting the prognosis of patients with oral squamous cellcar cinoma (OSCC). Methods: Retrospective study of 55 cases of surgical treatment of primary oral squamous cell carcinoma patients with prognosis-related factors: age, gender, location of the disease, cervical lymph node metastasis, tumor cell differentiation and so on. Results: The average age of onset was 57.35 ± 12.02 years, with the highest recurrence rate (45.5%), the second tongue (44%), the third cheek (37.5%) and the best prognosis of lip cancer (0.0% ). Preoperative neck lymph node metastasis, tumor cell differentiation and prognosis. There was no significant correlation between the differentiation degree of tumor cells and lymph node metastasis before operation. Preoperative neck lymph node metastasis combined with poorly differentiated and prognosis. Conclusion: There is no significant correlation between the prognosis of oral squamous cell carcinoma and the site of disease. Poorly differentiated tumor and lymph node metastasis before surgery prone to recurrence and metastasis.