现代细胞生物学的发展揭示了恶性肿瘤的发生发展是致癌剂和促癌剂与易感机体相互作用,在体细胞水平上发生的一系列复杂过程,包括启动、促进、进展和转移各个阶段。但是只有在近年来分子生物学和基因工程技术迅猛进展的基础上,才能从细胞基因改变来认识癌变的确切机制和了解癌的本质。癌症的分子生物学基础为从根本上解决 The development of modern cell biology has revealed that the occurrence and development of malignant tumors is a series of complex processes that occur at the somatic cell level in the interaction of carcinogens and cancer promoters with susceptible organisms, including initiation, promotion, progression, and metastasis. However, only on the basis of rapid advances in molecular biology and genetic engineering technology in recent years, can we understand the exact mechanism of canceration and understand the nature of cancer from the genetic changes in cells. The fundamental molecular basis of cancer is to fundamentally solve