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目的:探讨换血术对高胆红素血症新生儿血液指标的影响,评价其疗效及安全性。方法:选择外周动静脉换血新生儿22例,整个换血过程中未用肝素,比较换血前后胆红素、血常规、电解质、凝血五项的变化情况。结果:换血前后血清总胆红素下降49.56%,白细胞、红细胞、血红蛋白、白蛋白、血小板、血钾、钠、镁水平均下降(P<0.001),血钙升高(P<0.05),凝血五项无明显变化(P>0.05)。结论:外周动静脉换血疗效好、操作简单,换血过程中需及时监测血常规和电解质等保证换血安全。
Objective: To investigate the effect of transplanting on the blood indexes of newborns with hyperbilirubinemia and to evaluate its efficacy and safety. Methods: Twenty-two newborns with peripheral arteriovenous shunts were selected. No heparin was used in the whole process of blood exchange. The changes of bilirubin, blood routine, electrolytes and coagulation before and after transfusions were compared. Results: Serum total bilirubin decreased 49.56% before and after transfusions, the levels of white blood cells, erythrocytes, hemoglobin, albumin, platelets, serum potassium, sodium and magnesium decreased (P <0.001) Five no significant changes (P> 0.05). Conclusion: Peripheral arteriovenous exchange transfusion is effective and easy to operate. It is necessary to monitor blood routine and electrolytes in time to ensure the transfusion safety.