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目的观察芩翘口服液联合利巴韦林注射液治疗小儿手足口病的疗效。方法选择手足口病患者123例随机分成两组,观察组63例采用口服芩翘口服液、静脉滴注利巴韦林注射液治疗;对照组60例给予静脉滴注利巴韦林注射液治疗,两组疗程3~5 d。观察两组患者用药后临床症状及体征改善时间。结果观察组热退时间、皮疹消退时间明显少于对照组,1个疗程结束后观察组总有效率为95.2%,对照组总有效率为80%,两组比较差异有统计学意义(P<0.05),两组治疗过程中无副反应发生。结论芩翘口服液联合利巴韦林注射液治疗手足口病具有疗程短、见效快、毒副反应少等优点,值得临床推广使用。
Objective To observe the efficacy of Qinqian oral liquid and ribavirin injection in the treatment of hand-foot-mouth disease in children. Methods 123 cases of hand, foot and mouth disease were randomly divided into two groups, 63 cases in the observation group were treated with orally Qinqian oral solution and ribavirin injection. In the control group, 60 cases were given intravenous infusion of ribavirin injection , Two courses of treatment of 3 ~ 5 d. The clinical symptoms and signs of the two groups were observed after treatment. Results The remission time of the observation group was significantly shorter than that of the control group. The total effective rate was 95.2% in the observation group and 80% in the control group after one course of treatment. The difference between the two groups was statistically significant (P < 0.05). No side effects occurred during the two groups. Conclusion Qinqiao orally combined with ribavirin injection for the treatment of hand, foot and mouth disease has the advantages of short course of treatment, quick response, less side effects and is worthy of clinical promotion and use.