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目的 探讨严重急性呼吸综合征患者的临床特征、X线表现及其治疗方法。方法 回顾分析5 2例确诊严重急性呼吸综合征患者的临床资料。结果 5 2例患者临床发病期全部出现发热 (10 0 % ) ,寒战(6 7.3% ) ,咳嗽 (5 7.7% ) ,肌肉痛 (5 9.6 % )。原始X线胸片中 4 4例有异常改变 ,表现为片状阴影 ,下肺区(6 3.6 % )和右肺 (6 1.4 % )较易受累 ,单发病灶 2 3例 ,多发或双侧病灶 2 1例 ,无空洞和胸腔积液表现。治疗期 19例表现为重症严重急性呼吸综合征 ,使用无创呼吸机 10例 (CPAP 4~ 8cmH2 O) ,部分患者X线变化和临床症状、体征发展不同步。结论 患者病情快速发展变化 ,单侧多发或双侧受累 ,无空洞及胸腔积液是严重急性呼吸综合征患者典型的X线表现。早期使用无创呼吸机和皮质类固醇激素可降低患者的病死率。
Objective To investigate the clinical features, X-ray findings and treatment of patients with severe acute respiratory syndrome. Methods Retrospective analysis of 52 cases of patients diagnosed with severe acute respiratory syndrome clinical data. Results All 52 patients experienced fever (10 0%), chills (6 7.3%), cough (5 7.7%) and muscle pain (59.6%) at clinical onset. There were abnormal changes in 44 cases of primary X-ray, which showed flaky shadows. The lower lungs (3.6%) and right lungs (6.4%) were more likely to be involved, with single lesions (23%), multiple or bilateral Lesions in 21 cases, no cavities and pleural effusion performance. In the treatment period, 19 cases showed Severe Severe Acute Respiratory Syndrome. Ten patients (CPAP 4 ~ 8cmH2O) were used noninvasive ventilator. Some patients had different X-ray, clinical symptoms and signs. Conclusion The rapid development of patients with multiple unilateral or bilateral involvement, no cavities and pleural effusion is a typical case of severe acute respiratory syndrome X-ray findings. Early use of non-invasive ventilator and corticosteroids reduce patient mortality.