论文部分内容阅读
目的了解幽门螺旋杆菌(HP)感染对缺铁性贫血(IDA)发病的影响,观察抗HP治疗对改善贫血的效果。方法采用13C呼气试验检测105例IDA患者的幽门螺杆菌并对HP阳性患者行根除HP治疗,观察其血红蛋白上升情况及其他血液学指标的变化。结果本组60例HP检测阳性患者中,抗HP治疗后HP转阴52例,转阴率86.7%;HP根治的患者有35例(67.3%)贫血纠正,SF恢复正常。治疗后血液学指标有不同程度的改善。结论幽门螺杆菌感染可能是缺铁性贫血的一个致病因素,以HP阳性慢性胃炎作为惟一病因的IDA患者,根除HP可治愈IDA;对于临床上缺铁原因不明的IDA患者,应该注意检测HP感染的情况,给予有效的抗HP治疗。
Objective To investigate the effect of Helicobacter pylori (HP) infection on the incidence of iron deficiency anemia (IDA) and to observe the effect of anti-HP therapy on the improvement of anemia. Methods 13C breath test was used to detect Helicobacter pylori in 105 patients with IDA. HP-positive patients were treated with eradication of HP, and the changes of hemoglobin and other hematological indexes were observed. Results In the 60 patients with positive HP test, 52 cases of HP were negative after anti-HP treatment, with a negative conversion rate of 86.7%; 35 cases (67.3%) of HP-cured patients had anemia corrected and SF returned to normal. After treatment hematological indicators have varying degrees of improvement. Conclusions Helicobacter pylori infection may be a causative factor for iron deficiency anemia. IDA patients with HP-positive chronic gastritis as the only cause can eradicate IDA by eliminating HP. IDA patients with unknown causes of iron deficiency should pay attention to the detection of HP Infection, give effective anti-HP treatment.