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目的探讨银杏达莫对不稳定型心绞痛(unstable angina pectoris,UAP)患者临床疗效及作用机制。方法对照组UAP患者32例应用常规治疗,治疗组30例在常规治疗基础上加用银杏达莫。比较两组患者治疗前后的hsCRP水平及心绞痛缓解程度。结果两组患者hsCRP水平均较治疗前下降,以治疗组下降更明显,治疗组心绞痛缓解情况亦明显优于对照组,与对照组相比差异有统计学意义(P<0.05)。结论银杏达莫能有效治疗UAP,抑制冠脉粥样斑块的炎性反应是其作用机制之一。
Objective To investigate the clinical effect and mechanism of gingivald in patients with unstable angina pectoris (UAP). Methods 32 cases of UAP patients in the control group were treated with conventional therapy. 30 cases in the treatment group were given ginkgo-dipyridamole on the basis of routine treatment. The levels of hsCRP and angina pectoris in both groups before and after treatment were compared. Results The levels of hsCRP in both groups were significantly lower than those before treatment. The decrease in the treatment group was more pronounced. The relief of angina pectoris in the treatment group was also significantly better than that in the control group. The difference was statistically significant (P <0.05). Conclusion Ginkgo biloba can effectively treat UAP and inhibit the inflammatory reaction of coronary atherosclerotic plaque.