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目的：探讨高龄尿毒症患者尸体肾移植手术的适应证、免疫抑制剂的应用和T细胞亚群、ICAM—1对急性排斥的监测治疗及并发症的防治。方法：对37例60～71岁尿毒症患者进行尸体肾移植手术，术后进行各项指标监测。结果：1年人／肾存活率为83．8％／75．7％；3年为78．6％／67．9％，5年为72．2％／55．6％。急性排斥发生率为24．3％。结论：合理应用免疫抑制剂及监测和治疗急性排斥反应，降低术后并发症是提高高龄患者肾移植存活率的重要因素。
Objective: To investigate the indications of cadaveric kidney transplantation in elderly patients with uremia, the application of immunosuppressive agents and T cell subsets, the monitoring and treatment of acute rejection by ICAM-1 and the prevention and treatment of complications. Methods: 37 cases of uremia patients aged 60 to 71 years were subjected to cadaveric kidney transplantation. All indexes were monitored after operation. Results: The 1-year survival rate of human / kidney was 83.8% / 75.7%, 3 years was 78.6% / 67.9%, and 5 years was 72.2% / 55.6%. The incidence of acute rejection was 24.3%. Conclusion: The rational use of immunosuppressive agents and monitoring and treatment of acute rejection, reduce postoperative complications is to improve the survival of elderly patients with renal transplantation an important factor.