论文部分内容阅读
目的评价中国(未包括香港、澳门特别行政区和台湾地区,下同)2006年麻疹实验室网络的运转情况。方法分析全国2006年麻疹实验室网络监测数据库、中国疾病预防控制中心(CDC)病毒病预防控制所国家麻疹实验室血清学和病毒学监测数据库,评价中国麻疹实验室网络运转的各项指标。结果①血清学监测:全国2006年共采集麻疹血清学标本60173份,标本采集率为57.44%;采集合格标本并有实验室结果的50197份,占采集标本总数的83.42%。对其中858起疫情爆发中的794起,经实验室证实为麻疹爆发;对84起疫情爆发中的73起,经实验室证实为风疹爆发。②病毒学监测:2006年14个省(自治区、直辖市,下同)CDC麻疹实验室共送检196株麻疹病毒,经证实全部为麻疹野病毒H1基因型中的H1a亚型;7个省CDC麻疹实验室共送检17株阳性风疹病毒,除来自同一起爆发的2株四川省风疹病毒为2B基因型外,其余均为1E基因型。③实验室网络质量控制:2006年国家麻疹实验室通过了世界卫生组织的职能考核和现场认证;所有省CDC麻疹实验室通过了由国家麻疹实验室组织的血清标本复核;湖南、云南、福建、新疆、四川、安徽、内蒙古、江苏省CDC麻疹实验室通过了实验室现场考核。结论中国2006年麻疹实验室网络运转良好,并建立了比较健全的质量控制体系,规范了标本采集、血清学检测、细胞培养、病毒分离等标准方法,为2012年消除麻疹奠定了实验室基础。
Objective To evaluate the operation of the measles laboratory network in China (excluding Hong Kong, Macao Special Administrative Region and Taiwan, the same below) in 2006. Methods The database of measles laboratory network monitoring in China, serological and virological monitoring database of the national measles laboratory of the Chinese Center for Disease Control and Prevention (CDC) virus prevention and control were analyzed in 2006 to evaluate the indicators of the network operation of the measles laboratory in China. Results ① Serological surveillance: A total of 60,173 measles serological samples were collected nationwide in 2006, with a sample collection rate of 57.44%. A total of 50,197 samples were collected and accounted for 83.42% of the total number of samples collected. Among them, 794 out of 858 outbreaks were confirmed by the laboratory as measles outbreaks; 73 out of 84 outbreaks were laboratory confirmed as outbreaks of measles. ② virological monitoring: In 2006, 14 provinces (autonomous regions and municipalities, the same below) CDC measles laboratory sent a total of 196 measles virus, confirmed that all of the H1a subtype of measles wild-type virus H1; 7 provinces CDC Measles laboratory were seized a total of 17 positive rubella virus, except from the same two cases of Sichuan Province rubella virus is 2B genotype, the rest are 1E genotype. ③ Laboratory network quality control: In 2006, the national measles laboratory passed the functional examination and field certification of the World Health Organization; all provincial CDC measles laboratories passed the review of serum samples organized by the National Measles Laboratory; Hunan, Yunnan, Fujian, Xinjiang, Sichuan, Anhui, Inner Mongolia, Jiangsu Province, CDC measles laboratory passed the laboratory site assessment. Conclusion The Chinese measles laboratory network operated well in 2006 and a sound quality control system was established. Standard methods such as specimen collection, serological detection, cell culture and virus isolation were standardized, laying a laboratory foundation for eliminating measles in 2012.