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为提高卵巢癌的疗效,增加腹腔内抗癌药物的浓度并延长其对肿瘤的作用时间,使用抗癌复合剂:制成含有环磷酰胺、5-氟尿嘧啶和阿霉素的醋酸纤维素颗粒,放入腹腔内,抗癌药物释放时间取决于颗粒的大小,一般为10～25天。作者用大鼠制成腹水型卵巢癌模型进行实验,结果表明,抗癌复合剂能增强抗癌作用;对于生长较快的肿瘤,应使用颗粒较小的抗癌复合剂,以加快抗癌药的释放;相反,对生长较慢的肿瘤则使用颗粒较大者。1986～1990年,作者用抗癌复合剂治疗Ⅲ～Ⅳ期卵巢癌48例,平均年龄48岁。所用抗
In order to improve the efficacy of ovarian cancer, increase the concentration of intraperitoneal anticancer drugs and prolong the action time of the tumor, the anticancer agent is used to make cellulose acetate granules containing cyclophosphamide, 5-fluorouracil and doxorubicin, Into the abdominal cavity, anti-cancer drug release time depends on the size of the particles, usually 10 to 25 days. The authors used rat ascites ovarian cancer model experiments showed that anticancer agents can enhance the anti-cancer effect; for fast-growing tumors, the use of smaller particles of anticancer agents, to speed up the anticancer drug Release; on the contrary, the slower growth of the tumor is the use of larger particles. From 1986 to 1990, the authors treated 48 patients with stage III-IV ovarian cancer with anticancer agents, with an average age of 48 years. Anti-used