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本研究检测了１８例脑出血患者急性期血与脑脊液（ＣＳＦ）肿瘤坏死因子（ＴＮＦ）水平，结果发现脑出血急性期血与ＣＳＦＴＮＦ含量均显著升高，ＣＳＦＴＮＦ水平升高更为明显。提示受损的脑组织是ＴＮＦ活性增高的主要原因，ＴＮＦ参与了脑出血急性期的炎性反应过程。
In this study, 18 patients with acute cerebral hemorrhage were tested for levels of tumor necrosis factor (TNF) in blood and cerebrospinal fluid (CSF). The levels of blood and CSFTNF in acute phase of cerebral hemorrhage were significantly increased, while the level of CSFTNF increased more significantly. It suggested that impaired brain tissue is the main reason for the increase of TNF activity. TNF participates in the inflammatory reaction during the acute phase of cerebral hemorrhage.