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促红细胞生成素(EPO)是一种造血细胞生长因子,以往主要用于治疗多种原因所致的贫血。研究发现EPO受体广泛分布于各种非造血组织,其中包括心脏组织。最近的研究提示,EPO对心肌梗死、缺血再灌注损伤及阿霉素心肌损害等具有保护作用。
Erythropoietin (EPO) is a hematopoietic growth factor that has been used primarily to treat anemia of many causes. The study found that EPO receptors are widely distributed in a variety of non-hematopoietic tissues, including heart tissue. Recent studies suggest that EPO has a protective effect on myocardial infarction, ischemia-reperfusion injury and myocardial damage of doxorubicin.