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研究表明,炎症已经成为急性冠状动脉(冠脉)综合征(ACS)发生发展过程中的核心因素,不稳定性心绞痛患者中性粒细胞明显升高,髓过氧化物酶(myeloperoxidase,MPO)的含量有明显变化。而 MPO 具有促炎、促动脉粥样硬化的作用,影响粥样斑块的稳定性,并通过增大氧化应激而引起ACS。本研究旨在探讨在 ACS 患者中 MPO 活性变化以及与肌钙蛋白Ⅰ(TnI)之间的关系。1.资料和方法:选择2005年8月至2006年9月在本院抢救中心行冠脉造影术患者共318例,冠脉造影正常组82
Studies have shown that inflammation has become a core factor in the development and progression of acute coronary syndrome (ACS). Neutrophils are significantly elevated in patients with unstable angina and myeloperoxidase (MPO) Significant changes in content. While MPO has a pro-inflammatory, pro-atherogenic role, affecting the stability of atherosclerotic plaque, and by increasing oxidative stress caused by ACS. The aim of this study was to investigate the relationship between changes in MPO activity and troponin I (TnI) in patients with ACS. 1. Materials and Methods: A total of 318 patients undergoing coronary angiography at our rescue center from August 2005 to September 2006 were selected. Coronary angiography group 82