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目的研究脑梗塞患者血小板数目，体积和功能变化。方法随机选择９７例脑梗塞患者测定急性期和恢复期血小板数目，体积，粘附和聚集功能，３０例健康人作为正常对照组。结果脑梗塞急性期血小板体积，粘附率和聚集率均高于对照组（Ｐ＜０．０１）；而血小板数目和解聚率均低于对照组（Ｐ＜０．０１）。恢复期血小板体积，粘附率，５分钟聚集率虽比急性期降低，但仍高于对照组（Ｐ＜０．０１），而血小板数目及解聚率与对照组相似。大面积梗塞血小板，粘附率和最大聚集率均高于小面积梗塞（Ｐ＜０．０１）；多元逐步回归分析血小板体积，最大聚集率与脑梗塞容积呈正相关。结论脑梗塞患者血小板消耗，体积增大，功能亢进，血小板体积与最大聚集率和梗塞面积有关
Objective To study the changes of platelet count, volume and function in patients with cerebral infarction. Methods A total of 97 patients with cerebral infarction were selected randomly to determine the number of platelets, volume, adhesion and aggregation in acute phase and convalescent phase, and 30 healthy individuals as normal control group. Results In the acute stage of cerebral infarction, the platelet volume, the adhesion rate and the aggregation rate were all higher than those in the control group (P <0.01). The number of platelets and the rate of depolymerization were both lower than those in the control group (P <0.01). The platelet volume and adhesion rate in convalescent phase were lower than those in control group at 5 minutes (P <0.01), while the number of platelets and disaggregation rate were similar to those in control group. Large area infarction platelets, adhesion rate and maximum aggregation rate were higher than small area infarction (P <0.01). Multiple stepwise regression analysis of platelet volume, maximum aggregation rate and cerebral infarction volume was positively correlated. Conclusion Cerebral infarction patients with platelet consumption, volume increase, hyperthyroidism, platelet volume and maximum aggregation rate and infarct size