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目的:了解本地区新生儿G-6-PD缺陷的发病率。方法:采用G6PD/6PGD比值法对2000~2005年在富川县妇幼保健院出生的新生儿进行G-6-PD测定。结果:筛查出新生儿G-6-PD缺陷90例,总发病率为3.59%。男性发病率5.64%,女性为1.64%;城市发病率为3.66%,乡村为3.58%;汉族发病率为1.83%,瑶族为5.18%。结论:男性发病率高于女性,差异有极显著性(P<0.001);城乡之间发病率比较,差异无显著性(P>0.05);瑶族与汉族间发病率比较,差异有显著性(P<0.05)。
Objectives: To understand the incidence of neonatal G-6-PD deficiency in this region. Methods: G-6-PD was measured in neonates born in Fuchuan MCH from 2000 to 2005 by G6PD / 6PGD ratio method. Results: Ninety cases of neonatal G-6-PD were screened out, with a total incidence of 3.59%. The incidence of males was 5.64% and that of females was 1.64%. The incidence was 3.66% in urban areas and 3.58% in rural areas. The incidence of Han was 1.83% and that of Yao was 5.18%. Conclusion: The morbidity of males is higher than that of females, and the difference is significant (P <0.001). There is no significant difference in morbidity between urban and rural areas (P> 0.05). The morbidity between Yao and Hans is significant P <0.05).