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目的盐酸曲马多针在产程活跃期中的镇痛效果和安全性。方法临产初产妇240例,均无妊娠合并症和并发症,随机分成观察组和对照组,每组120例,观察组为曲马多组,对照组未用药,采用安慰抚触、指导等帮助,在产程活跃期宫口开大2~3 cm时,观察组采用盐酸曲马多针100 mg肌内注射,观察两组的镇痛效果、产程进展、不良反应、对新生儿的影响。结果在镇痛效果方面观察组优于对照组,差异有统计学意义(P<0.05),产程进展与分娩结局观察组与对照组对比,差异无统计学意义(P>0.05);不良反应发生率差异无统计学意义(P>0.05);新生儿Apgar评分两组比较,差异无统计学意义(P>0.05)。结论盐酸曲马多针对缓解分娩疼痛有效,不良反应少,对母婴无不良影响。
Objective To observe the analgesic effect and safety of tramadol hydrochloride in the active phase of labor. Methods A total of 240 primiparae patients were absent. All of them had no pregnancy complications and complications. They were randomly divided into observation group and control group, with 120 cases in each group. The observation group was tramadol group. The control group was given no medication, , During the active phase of labor, the cervix opened 2 ~ 3 cm wide. The observation group was given intramuscular injection of tramadol hydrochloride 100 mg intraperitoneally to observe the effects of analgesia, labor progress, adverse reactions and newborns on the newborns. Results Compared with the control group, the observation group was superior to the control group in analgesic effect (P <0.05), and there was no significant difference between the observation group and the control group in labor progress and delivery outcome (P> 0.05). Adverse reactions There was no significant difference between the two groups (P> 0.05). Neonatal Apgar score was no significant difference between the two groups (P> 0.05). Conclusion Tramadol hydrochloride is effective in alleviating pain during childbirth and has few side effects and no adverse effects on maternal and infant.