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目的观察我院传染科使用派罗欣注射液不良反应发生的情况,为临床医师用药提供参考。方法从传染科2008年1月至2010年12月使用派罗欣注射液的住院病例中选取62例,所选病例用药前体温(T)和血常规均正常,统计其用药后主要不良反应,对有关数据进行评价分析。结果使用派罗欣注射液的62例住院病人中,有32例用药后出现流感样症状,24例出现血液系统损害(白细胞、血小板减少),其他不良反应6例。结论临床医师在使用派罗欣注射液时应注意其常见的发热、畏寒、肌痛、头痛等类似流感样症状及血液系统损害(白细胞、血小板减少)。
Objective To observe the adverse reactions of Pegasys injection used in the Department of Infectious Diseases in our hospital to provide references for clinicians to use drugs. Methods Sixty-two inpatients were selected from Department of Infectious Diseases from January 2008 to December 2010 using Pegasys injection. The body temperature (T) and blood routine of the selected cases were normal before treatment, and the main adverse reactions were observed after treatment. Evaluation of the data for analysis. Results Of the 62 inpatients using Pegasys injection, 32 developed flu-like symptoms after treatment, 24 had hematologic (leukopenia, thrombocytopenia) and 6 other adverse reactions. Conclusions Clinicians should pay attention to the common flu-like symptoms and blood system damage (white blood cells, thrombocytopenia) when using Pegasys injection in patients with fever, chills, myalgia and headache.