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目的 分析和探讨垂体ACTH腺瘤的诊断和治疗。方法 对我科收治的 2 9例垂体ACTH腺瘤患者的临床特点和治疗效果进行了回顾性分析。结果 垂体ACTH微腺瘤的诊断较为困难 ,有库欣氏综合症表现的患者 ,辅以血清ACTH、地塞米松抑制试验等并结合影像学资料方可确诊 ,经蝶手术切除肿瘤复发率仅为 6 9%。结论 垂体ACTH腺瘤的诊断须依靠临床表现、实验室检查和影像学检查等。经蝶手术切除肿瘤是治疗垂体ACTH腺瘤的首选方法
Objective To analyze and explore the diagnosis and treatment of pituitary ACTH adenoma. Methods The clinical features and therapeutic effects of 29 cases of pituitary ACTH adenoma treated in our department were retrospectively analyzed. Results Pituitary ACTH micro-adenoma diagnosis is more difficult, patients with Cushing’s syndrome performance, supplemented with serum ACTH, dexamethasone inhibition test combined with imaging data before diagnosis, transsphenoidal surgery tumor recurrence rate was only 6 9%. Conclusion The diagnosis of pituitary ACTH adenoma depends on clinical manifestations, laboratory tests and imaging studies. Transplantation of the tumor by transsphenoidal surgery is the preferred method of treatment of pituitary ACTH adenoma