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目的探讨HBsAg ,CEA与结直肠癌肝转移的关系。方法 :回顾性分析二院 1990～ 1995年间收治的 5 82例结直肠癌病例 ,对术前HBsAg和CEA进行过测定 ,分别观察它们与肝转移之间的关系。结果 :发现HB sAg、(+)结直肠癌病例的肝转移明显低于HBsAg(- )病例 (P <0 .0 5 ) ;CEA(+)结直肠癌病例与CEA(- )病例的肝转移率之间无明显差别 (P >0 .0 5 ) ,但CEA(+)病例的 5年生存率 31%明显低于CEA(- )病例的84 % (P <0 .0 1)。结论 :结直肠癌较少转移至感染乙肝的肝脏 ,CEA不能作为判断肝转移倾向的指标 ,可以作为判断结直肠癌预后的指标之一。
Objective To investigate the relationship between HBsAg, CEA and liver metastasis of colorectal cancer. Methods: A retrospective analysis of 5 82 cases of colorectal cancer treated in our hospital from 1990 to 1995 was performed. The preoperative HBsAg and CEA were measured and their relationship with liver metastasis was observed. Results: The liver metastases of HBsAg and (+) colorectal cancer cases were significantly lower than those of HBsAg (-) cases (P <0.05); liver metastases of CEA (+) colorectal cancer cases and CEA (-) cases There was no significant difference between the two groups (P> 0.05), but the 5-year survival rate was significantly lower in CEA (+) 31% than in CEA (-) 84% (P <0.01). CONCLUSIONS: Colorectal cancer is less likely to metastasize to the liver infected with hepatitis B, and CEA can not be used as a predictor of liver metastasis. It can be used as an indicator of the prognosis of colorectal cancer.