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本文报告一例典型小儿皮肌炎,血清中有抗横纹肌抗体,肌肉活检在肌膜有IgG沉积,用强的松和免疫抑制剂长期治疗无效,采用血浆交换疗法获得成功.病例报告:15岁女孩,1975年6月发病,有典型皮损,肌无力,SGOT169单位,CPK69单位(均高于正常值),肌肉活检阳性,肌电图示神经肌病型,确诊为皮肌炎.服强的松20～70毫克/日无效,又分别合用6-MP及MTX各数月亦无效.在血浆交换前9月,病人曾用强的松30毫克/日,环磷酰胺100
This article reports a case of pediatric dermatomyositis with anti-rhabdomyol antibodies in serum and muscle biopsy with IgG deposition on the muscular membrane, long-term treatment with prednisone and immunosuppressive agents, successful with plasma exchange therapy Case Report: 15-year-old girl , The onset in June 1975, there are typical lesions, muscle weakness, SGOT169 units, CPK69 units (were higher than normal), muscle biopsy positive, electromyography showed neuromyopathy, diagnosed as dermatomyositis. Song 20 ~ 70 mg / day invalid, but also combined with 6-MP and MTX each month also invalid.In September before plasma exchange, patients had prednisone 30 mg / day, cyclophosphamide 100