泮托拉唑钠是一种新型抗溃疡的质子泵抑制剂(Proton pump inhibitors,PPIs),对胃质子泵直接作用[1-2],抑制胃酸分泌,可有效治疗胃溃疡和十二指肠溃疡。与传统的抗酸剂和H2受体阻断剂相比,泮托拉唑钠有着更有效,更快起效和副作用更少的特点[3-4]。此外,在弱酸性的环境下,泮托拉唑比奥美拉唑和兰索拉唑等PPIs类抑制剂更稳定,在体内的生物 Pantoprazole sodium is a new type of anti-ulcer proton pump inhibitors (PPIs) that exert a direct effect on the gastric proton pump [1-2] and inhibit gastric acid secretion, which can effectively treat gastric ulcer and duodenum ulcer. Compared with traditional antacids and H2 receptor blockers, pantoprazole sodium has more effective, faster onset of action and fewer side effects [3-4]. In addition, pantoprazole is more stable than PPIs such as omeprazole and lansoprazole in a weakly acidic environment. In vivo,