速激肽(P 物质,神经激肽 A,神经肽 K)和降钙紊基因相关肽共存于感觉神经元中,其神经末梢中枢端止于脊髓背角,外周端止于内脏器官和皮肤粘膜等组织。刺激感觉神经,这两类神经肽即可从末梢端释放。速激肽和降钙素基因相关肽在感觉神经外周端的释放引起一系列的局部反应,如:毛细血管通透性增加、小动脉血管扩张、正性心率和正性肌力作用、非血管平滑肌张力的改变以及囱主神经节上的慢兴奋突触后电位。 Tachykinins (substance P, neurokinin A, neuropeptide K) and calcitonin gene-related peptides coexist in sensory neurons whose central terminal ends terminate in the spinal dorsal horn and whose peripheral ends terminate in internal organs and skin mucosa Other organizations. Stimulate the sensory nerve, these two types of neuropeptides can be released from the distal tip. The release of tachykinins and calcitonin gene-related peptides at the peripheral sensory nerve leads to a series of local reactions such as increased capillary permeability, arteriolar dilatation, positive heart rate and inotropic effects, non-vascular smooth muscle tone Changes as well as slow excitatory postsynaptic potentials on the hilar neurons.