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目的:观察加味麻黄附子细辛汤联合富马酸福莫特罗干粉吸入治疗老年支气管哮喘的临床疗效。方法:选取120例老年支气管哮喘患者为研究对象,随机分为对照组与观察组,每组60例。对照组采用小剂量富马酸福莫特罗粉吸入剂吸入治疗,观察组采取加味麻黄附子细辛汤联合小剂量富马酸福莫特罗粉吸入剂吸入治疗。观察2组临床症状的缓解时间及治疗前后肺功能指标[1秒用力呼气容积(FEV1)、最大呼气流量(PEF)]的变化,评估治疗效果。结果:观察组咳嗽、喘息、胸闷缓解时间均短于对照组(P<0.05)。治疗后,2组FEV_1及PEF均较治疗前升高(P<0.05),观察组的2项肺功能指标水平均比对照组升高更显著(P<0.05)。观察组治疗总有效率98.33%,高于对照组的80.00%,差异有统计学意义(P<0.05)。结论:加味麻黄附子细辛汤联合富马酸福莫特罗粉吸入剂吸入治疗老年支气管哮喘,临床疗效显著,可有效改善患者的各项临床症状及肺功能。
Objective: To observe the clinical effects of Modified Mahuang Fuzi Xixin Decoction combined with formoterol fumarate powder inhalation in the treatment of elderly bronchial asthma. Methods: 120 elder patients with bronchial asthma were selected as study object and randomly divided into control group and observation group, 60 cases in each group. The control group was treated with low-dose formoterol fumarate inhalation, and the observation group was treated with flavored ephedrine fucufloxacin combined with low-dose formoterol fumarate inhalation. The relief of clinical symptoms and the change of pulmonary function index (forced expiratory volume in one second (FEV1), maximum expiratory flow (PEF)] before and after treatment were observed to evaluate the therapeutic effect. Results: The cough, wheezing and chest tightness in the observation group were all shorter than those in the control group (P <0.05). After treatment, FEV_1 and PEF in both groups were significantly higher than those before treatment (P <0.05). The two indexes in the observation group were significantly higher than those in the control group (P <0.05). The total effective rate of the observation group was 98.33%, which was higher than that of the control group (80.00%), the difference was statistically significant (P <0.05). Conclusion: Modified ephedrafuzi Asarum combined with formoterol fumarate powder inhalation inhalation treatment of elderly bronchial asthma, the clinical effect is significant, can effectively improve the patient’s clinical symptoms and pulmonary function.