患儿,女性,12岁。因贫血、白细胞低下及肝脾肿大3个月,于1985年8月26日入院。经骨髓穿刺证实为急性淋巴细胞性白血病(L_2型)。5个月中接受VCP、VP、MTX及6MP等治疗,好转出院。化验检查:蛋白电泳、A1b79%,γ6.8%,其中它无明显异常。住院后1个月发现手、腋下、腹股沟等处皮肤粗厚,其它部位有瘙痒性丘疹,请皮肤科会诊发现皮肤损害除头面部和足底外全身泛发。在双手掌及手背为密 Children, women, 12 years old. Due to anemia, leukopenia and hepatosplenomegaly 3 months, admitted on August 26, 1985. Bone marrow puncture confirmed acute lymphoblastic leukemia (L 2 type). 5 months to accept VCP, VP, MTX and 6MP and other treatment, improved discharged. Laboratory tests: protein electrophoresis, A1b79%, γ6.8%, of which there is no obvious abnormalities. 1 month after hospitalization found that hands, armpits, groin and other parts of the skin thick, and other parts of pruritic papules, dermatology consultation, please find the skin damage head and face and body outside the general body hair. In both hands and back of the palm is dense