在以显微注射法制备10多种基因构件的转基因小鼠的过程中,对所有的转基因胚胎受体小鼠(ICR)的妊娠期及其产仔存活率进行了观察.结果:98只怀孕受体小鼠中,75只在移植后19~21D产仔,产仔存活率为93.5％(374/400);16只在移植后22~24D自然分娩,全部为死仔;7只在移植后22~23D行剖宫产术,产仔存活率为60.7％(17/28).以上结果表明:受体母鼠的怀孕期与正常小鼠基本一致;过期妊娠受体鼠自然分娩,其产仔存活率极低(0％),若采用剖宫取胎再寄养的方法,可大大提高过期妊娠受体鼠的产仔存活率.“,”The pregnancy of the recipients and survival rate of founder mice during the pro duction of transgenic mice with twelve genes were studied. The results showed th at 75 of 98 pregnant recipiens had parturition 19～21 days after embryo transfer ence and the survival rate of their progenies was 93.5%(374/400). 16 of 98 preg nancy recipients had natural parturition 22～24 days after embryo transference, 7 of 98 pregnancy recipients had parturition by cesarean section 22～23 days aft er embryo transference, and t...