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目的观察米索前列醇片用于早期妊娠人工流产的疗效。方法选择宫内孕40～70天,自愿要求人工流产终止妊娠的孕妇160例,随机分为两组,每组80例。观察组阴道后穹窿处置入米索前列醇片400μg,3 h后行人工流产术;对照组不用任何药物,直接行人工流产术。观察两组患者宫颈软化扩张程度、术中出血量、手术时间、以及人流综合征的发生率以及受术者痛苦程度。结果观察组宫颈软化扩张比例明显增高,术中出血量减少,手术时间缩短,人流综合征发生率明显降低,受术者痛苦明显减轻。结论米索前列醇用于人工流产安全有效,可广泛临床应用。
Objective To observe the efficacy of misoprostol for abortion in early pregnancy. METHODS: Intrauterine pregnancy was performed for 40-70 days. 160 pregnant women who voluntarily requested termination of pregnancy induced by induced abortion were randomly divided into two groups (n = 80 in each group). Observation group vaginal fornix into misoprostol 400μg, 3 h after abortion; the control group without any drugs, direct abortion. The degree of cervix softening and expansion, intraoperative blood loss, operation time, the incidence of flow syndrome and the pain degree of the patients were observed. Results The ratio of cervical softening and dilatation in the observation group was significantly higher, the intraoperative blood loss decreased, the operation time shortened, the incidence of the flow syndrome was significantly reduced, and the pain relief of the surgeon was significantly reduced. Conclusion Misoprostol is safe and effective for induced abortion and it can be widely used in clinic.