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目的了解母婴同室新生儿黄疸的发生规律,探讨新生儿高胆红素血症的诱发原因。方法研究对象为2000年6月～8月份我院母婴同室新生儿206例,采用经皮胆红素测定仪测定生后7天内的胆红素值。对出现高胆红素的新生儿进行相关因素分析。结果生后24小时内胆红素大于85umol/L(5mg/dl)者32例,其中有8例在未来一周内出现高胆红素血症。7日内胆红素高于正常值者共43例,有17例母乳分泌少,婴儿排便次数少,有12例孕周大于40周,并伴有羊水少或胎盘钙化。本组病例胆红素出现的峰值时间多为生后4～5天,平均峰值174umol/L(10.2mg/dl),无一例在生后第一天出现峰值。结论生后24小时内胆红素水平较高(>85umol/L)的新生儿应引起重视。孕周大于40周,且其母亲胎盘功能减退者应注意高胆红素血症的发生。母亲泌乳量少,新生儿生后三天内排便次数少者,高胆红素血症的发病率较高。
Objective To understand the occurrence of neonatal jaundice in the same room and explore the causes of hyperbilirubinemia. Methods The study was performed on 206 neonates with the same mothers and their infants in our hospital from June to August in 2000. The bilirubin value was measured within 7 days after transdermal bilirubin determination. Neonatal hyperbilirubinemia related factors analysis. Results 32 cases of bilirubin greater than 85umol / L (5mg / dl) within 24 hours after birth, of which 8 cases of hyperbilirubinemia in the next week. 7 days bilirubin higher than normal, a total of 43 cases, 17 cases of breast milk secretion less, the number of infant defecation less, 12 cases of gestational age greater than 40 weeks, accompanied by oligohydramnios or placental calcification. In this group, the peak time of bilirubin appeared mostly 4 to 5 days after birth, the average peak was 174umol / L (10.2mg / dl), and no peak appeared on the first day after birth. Conclusion Neonates with high bilirubin level (> 85umol / L) should pay attention to within 24 hours after birth. Pregnancy more than 40 weeks, and her mother’s placental function decline should pay attention to the occurrence of hyperbilirubinemia. Maternal lactation less, three days after birth neonatal defecation less, the incidence of hyperbilirubinemia higher.