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1目的 探讨老年糖尿病病人 QTd,JTd增加与其发生猝死的关系。 2方法 受检者常规测量 12导联心电图 QT及 JT间期。最长 QT间期或 JT间期减去最短 QT或 JT间期 ,即得 QTd或 JTd.比较对照组与糖尿病组 (猝死组与存活组 )的 QTd,JTd.3结果 老年糖尿病病人 QTd,JTd分别为 (78.2 4± 2 7.6 8) ms,(79.86±2 1.48) ms,而对照组分别为 (4 7.16± 18.2 7) ms,(4 6 .32± 2 0 .12 ) m s,两组比较差异有显著性 (t=6 .6 3,7.2 3,P<0 .0 0 1)。糖尿病猝死组 QTd,JTd分别为 (96 .5 6± 2 8.2 6 ) ms,(98.78± 30 .42 ) ms;存活组 QTd,JTd分别为 (5 9.2 7±19.14) m s,(6 0 .47± 2 1.5 2 ) ms,猝死组 QTd,JTd均明显长于存活组 ,差异有显著性 (t=5 .93,5 .5 8,P<0 .0 0 1)。 4结论 老年糖尿病病人猝死的发生随 QTd,JTd的延长而增加 ,提示 QTd,JTd延长是预测老年糖尿病病人猝死的一项有价值指标
1 Objective To investigate the relationship between the increase of QTd and JTd in elderly diabetic patients and its occurrence of sudden death. 2 Methods Subjects routinely measured 12-lead ECG QT and JT intervals. The QTd or JTd was obtained from the longest QT interval or JT interval minus the QTd or JT interval.The QTd and JTd.3 results of the control group and diabetic group (sudden death group and survival group) (78.2 4 ± 2 7.68) ms and (79.86 ± 2.148) ms, respectively, while the control group were (4.71 ± 18.2 7) ms and (46.32 ± 20.12) ms, respectively The difference was significant (t = 6.36, 7.23, P <0.001). The QTd and JTd were (96.56 ± 2.82 6) ms and (98.78 ± 30.42) ms in the patients with sudden death from diabetes, respectively. The QTd and JTd in survivors were (5 9.27 ± 19.14) ms and ± 2 1.52) ms, QTd and JTd in the sudden death group were significantly longer than those in the survival group (t = 5.993,5.58, P <0.01). Conclusions The incidence of sudden death in elderly diabetic patients increases with the prolongation of QTd and JTd, suggesting that prolongation of QTd and JTd is a valuable indicator of sudden death in elderly diabetic patients