【摘 要】
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A series of Benzisolselenazolone (BISA) derivatives were synthesized and evaluated for their antibacterial activities against E coli. by using LKB 2277 bio
【出 处】
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Wuhan University Journal of Natural Sciences
论文部分内容阅读
A series of Benzisolselenazolone (BISA) derivatives were synthesized and evaluated for their antibacterial activities against E coli. by using LKB 2277 bioactivity monitor. Other bioactivities were tested by the method of High Throughput Screening for pharmaceutical activity compounds(HTP) BISA derivatives 3b, at the concentration of 40 μg/mL, showed 100% antibacterial activity and 62% inhibition rate of aldose reductase(at the concentration of 5μg/mL). These new compound structures have determined by IR, 1H NMR and MS spectra.
A series of Benzisolselenazolone (BISA) derivatives were synthesized and evaluated for their antibacterial activities against E coli. By using LKB 2277 bioactivity monitor. Other bioactivities were tested by the method of High Throughput Screening for Pharmaceutical Activity Compounds (HTP) BISA derivatives 3b, at The concentration of 40 μg / mL showed 100% antibacterial activity and 62% inhibition rate of aldose reductase (at the concentration of 5 μg / mL). These new compound structures have determined by IR, 1H NMR and MS spectra.
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