目的分析狂犬病流行病学特征,探讨广西狂犬病防制的重点策略和措施。方法收集广西狂犬病大疫情资料和流行病学调查资料,用SPSS10.0统计分析软件进行分析。结果广西狂犬病疫情呈现发病率持续快速增长、地区分布不断扩展的趋势,疫情也由经济落后的桂西山区向经济较发达的桂东南、桂北地区扩散。发病时间与季节有关。88.5%的病例为狗伤所致,暴露后没有及时对伤口进行冲洗、消毒、清创的分别为68.0%、88.5%、91.5%,只有5.9%的病例暴露后全程接种狂犬疫苗,使用狂犬抗血清的只有1.7%。从广西抽查的狂犬疫苗中,80%不符合规定;收集89份健康犬的犬脑标本,检出病毒携带率为13.5%。结论广西狂犬病增长迅速,卫生部门应该将加强农村地区宣教、加强疫苗管理和开展狂犬暴露前免疫作为防控工作的重点。 Objective To analyze the epidemiological characteristics of rabies and to explore the key strategies and measures of rabies prevention in Guangxi. Methods Epidemiological data and epidemiological survey data of rabies in Guangxi were collected and analyzed by SPSS10.0 statistical analysis software. Results The incidence of rabies in Guangxi Province showed a sustained and rapid increase in the incidence and the distribution of the area was expanding. The epidemic also spread from the economically underdeveloped western Guangxi to the southeast Guangxi and northern Guangxi which were economically developed. The onset time and the season. 88.5% of the cases were caused by dog ​​wounds. After the wounds were exposed, the wounds were not washed, disinfected and debrided in 68.0%, 88.5% and 91.5% of the cases, respectively. Only 5.9% of the cases were vaccinated rabies vaccine. Only 1.7% of serum. Eighty percent of the rabies vaccine randomly selected from Guangxi did not comply with the regulations; 89 canine dogs’ brain samples were collected and the virus carrying rate was 13.5%. Conclusions Rapid growth of rabies in Guangxi, the health sector should strengthen education in rural areas, to strengthen vaccine administration and pre-immune rabies as a prevention and control work.