目的　观察甘露醇对自发性脑出血患者继续出血的影响。方法　将 182例经头颅CT确诊的发病在 6小时以内的脑出血患者随机分为甘露醇组和白蛋白组 ,观察两组用药后对继续出血的发生率和脑出血部位及有无高血压病史对继续出血的影响。结果　甘露醇组继续出血的发生率显著高于白蛋白组 (P <0 0 5 )。丘脑部位的继续出血率明显高于其它部位。有高血压病史者应用甘露醇后继续出血率高于白蛋白组。结论　自发性脑出血患者早期应用甘露醇能增加脑出血后继续出血的发生率 Objective To observe the effect of mannitol on patients with spontaneous cerebral hemorrhage continued bleeding. Methods A total of 182 patients with cerebral hemorrhage diagnosed by skull CT within 6 hours were randomly divided into mannitol group and albumin group. The incidence of continuous bleeding and the history of cerebral hemorrhage and the history of hypertension were observed after treatment The impact of continuing bleeding. Results The incidence of hemorrhage in mannitol group was significantly higher than that in albumin group (P <0.05). Thalamus continued bleeding rate was significantly higher than other parts of the site. Patients with a history of hypertension have higher rates of bleeding after administration of mannitol than those treated with albumin. Conclusion The early application of mannitol in patients with spontaneous intracerebral hemorrhage can increase the incidence of hemorrhage after intracerebral hemorrhage