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急性心肌梗死(AMI)即期使用溶栓治疗不仅能限制梗死范围,尚可改善预后,但使用各种溶栓药物,尤其是链激酶常可诱发血压下降,而使预后恶化。日前,关于溶栓治疗所致低血压的可能机理及其与临床的相关关系尚未清楚,对同期伍用β-阻滞剂在血压下降中的可能影响亦报道甚少,本文就此进行了分析。方法研究对象为1989~1990年间297例AMI患者(男220例,女77例,均龄69岁)。前壁AMI 113例,下壁AMI 116例。再梗死占30%,伴有心绞痛发作、高血压和糖尿病者分别为38%,
Acute myocardial infarction (AMI) immediate use of thrombolytic therapy can not only limit the infarct size, but also improve the prognosis, but the use of a variety of thrombolytic drugs, especially streptokinase can often induce blood pressure, leaving the prognosis worsened. Recently, the possible mechanism of thrombolytic therapy-induced hypotension and its relationship with the clinical remains unclear. The possible effect of β-blockers on blood pressure drop during the same period is also poorly documented. Methods The subjects were 297 AMI patients (220 males and 77 females, mean age 69 years) from 1989 to 1990. 113 cases of AMI in anterior wall and 116 cases of AMI in inferior wall. Recanalization accounted for 30%, with angina pectoris, hypertension and diabetes were 38%, respectively,