论文部分内容阅读
为探讨Ⅱ型糖尿病患者血小板活化状态的变化规律。应用流式细胞免疫学技术对63例 Ⅱ型糖尿病患者、 50例正常对照者血小板 CD6p进行定量检测,并经统计处理。 Ⅱ型糖尿病患者血小板 CD62p表达量明显高于对照组(P< 0.01),有血管并发症糖尿病患者 CD62p表达量显著高于无血管并发症组(P< 0.01),且无血管并发症组 CD62p表达量亦显著高于对照组(P< 0.01)。显示检测CD62p的表达量能预测糖尿病患者血小板活化状态,对防止糖尿病患者并发血管病变有重要意义。
To investigate the changes of platelet activation in patients with type 2 diabetes mellitus. Flow cytometry was used to quantitatively detect platelet CD6p in 63 patients with type 2 diabetes mellitus and 50 normal controls and the results were statistically analyzed. The expression of CD62p on platelet in type 2 diabetic patients was significantly higher than that in control group (P <0.01). The expression of CD62p in diabetic patients with vascular complications was significantly higher than that of non-diabetic patients (P <0.01) The expression of CD62p in disease group was also significantly higher than that in control group (P <0.01). CD62p expression showed that the detection of diabetic patients with platelet activation status, prevention of diabetic patients with vascular lesions of great significance.