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目的采用数据挖掘技术，从药物配伍的角度研究四君子汤类方的配伍规律。方法通过收集四君子汤类方959首，对数据进行预处理建立四君子汤类方数据库，使之能够用于数据挖掘。选用布尔关联规则的数据挖掘方法，从高频药物、药对、药组方面，揭示该四君子汤类方库的整体用药规律。结果建立了四君子汤类方数据库，运用布尔关联规则分析得到四君子汤类方库的高频药物、核心药对、核心药组。结论从药物配伍角度揭示四君子汤类方配伍规律，印证了布尔关联规则的数据挖掘方法适用于方剂配伍规律的研究。“,”Objective To research the compatibility disciplinarians of Si Jun Zi Tang serial Prescription and cor espondence rules by applicantion of data mining technology. Methods Pre-treat the data in order to built a 959-formula-Si Jun Zi Decoction database,which can be available for data mining.Select Boolean Association Rules to reseach the high frequency erbs、the couplet herbs、the herbal groups. Results The research built a 959-formula-Si Jun Zi Decoction database, found the high frequency erbs、the couplet herbs、the herbal groups of high frequency erbs、the couplet herbs,the herbal groups by Boolean Association Rules.Conclusion Reveal the rules of formula-herbs of Si Jun Zi Tang serial Prescription;This research found Boolean Association Rules can be use to reseach formulas’s compatibility disciplinarians.