目的探讨单侧椎动脉先天性发育不良超声检测参数与眩晕的关系。方法对单侧椎动脉先天性发育不良的309个病例,按照椎动脉发育不良的程度分为生理性全程细组(2.0mm<管径≤2.5mm)(208例)和生理性全程狭窄组(管径≤2.0 mm)(101例),按是否存在眩晕的症状分为眩晕组(186例)和非眩晕组(123例),超声检测椎动脉管径大小和血流动力学参数。结果 (1)单侧椎动脉先天性发育不良的患者眩晕发生率为60.19%(186/309),其中生理性全程细组眩晕发生率为50.48%(105/208),全程狭窄组眩晕发生率为80.20%(81/101),P<0.01。(2)生理性全程狭窄组患侧管径和椎间隙段收缩期峰值流速PSV均显著小于生理性全程细组,且阻力指数RI较大,差异均有统计学意义,P均<0.001。(3)非眩晕组的健侧椎动脉管径、PSV、舒张末期流速EDV数值均较眩晕组大,差异有统计学意义,P均<0.01。结论单侧椎动脉先天性发育不良与眩晕存在密切的关系,椎动脉管径狭窄到一定程度而对侧没有良好的代偿时,往往容易发生眩晕症状。椎动脉先天性发育不良可成为眩晕的独立影响因素。 Objective To investigate the relationship between vertigo and parameters of unilateral congenital hypoplasia of unilateral vertebral artery. Methods 309 patients with congenital dysplasia of unilateral vertebral artery were divided into three groups according to the degree of dysplasia of vertebral artery: total physiological group (2.0 mm