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本文对穿心莲制剂(新炎得平、含内酯和黄酮)的抗感染作用进行研究。结果表明,新炎得平可提高小鼠血清溶菌酶水平,增强腹腔巨噬细胞和中性粒细胞的吞噬能力,对家兔因注射致热原引起的发热反应有解热作用。然而,新炎得平对豚鼠血清补体总活性无影响,在体外亦无明显抗菌作用。
In this article, we investigated the anti-infective effects of Andrographis Paniculata (neo-inflammatory dipyridamole, lactone and flavonoids). The results showed that the new Yandeping can increase the level of serum lysozyme in mice to enhance the phagocytic capacity of peritoneal macrophages and neutrophils on the fever induced by injection of pyrogen in rabbits antipyretic effect. However, neo-yandeping had no effect on the total serum complement activity of guinea pigs and had no obvious antibacterial effect in vitro.