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目的 报告小儿肝脏恶性肿瘤的诊断和治疗。方法 近 10年间 2 6例小儿原发性肝脏恶性肿瘤病例。其中 ,14例经手术、介入等治疗列为治疗组。另 12例因病情严重放弃治疗 ,列为非治疗组。结果 2 6例肝脏恶性肿瘤中肝细胞癌 (HCC) 19例 (73.0 8% ) ,肝母细胞瘤 (HB) 5例 (19.2 3% ) ,恶性间叶瘤和横纹肌肉瘤各一例。 2 1例以 B超为首次肝脏肿瘤确诊方法。 HCC病例中 73.6 8%HBs Ag为阳性 ;非治疗组病儿均在一年内死亡 ;治疗组中 ,HCC切除治疗和介入治疗平均存活时间分别是 2 3.2和 2 .5个月。非HCC组肿瘤切除后多数长期存活。结论 1本组 HCC已显著多于 HB,乙肝病毒感染是重要原因。 2 HCC切除率低 ,预后差 ,但手术切除仍是延长病儿存活期的最好方法。 3非 HCC肿瘤的手术切除效果远好于 HCC。
Purpose To report the diagnosis and treatment of pediatric liver malignancies. Methods 26 cases of primary liver cancer in children in recent 10 years. Among them, 14 cases were treated by surgery, intervention and other treatment as treatment group. The other 12 cases due to serious illness to give up treatment, as a non-treatment group. Results Twenty - nine cases of hepatocellular carcinoma (HCC) were found in 19 cases (73.0%), 5 cases of hepatoblastoma (19.2%), one case of malignant mesenchymal tumor and rhabdomyosarcoma. Two hundred and twenty-one patients with B-ultrasound as the first diagnosis of liver cancer. In HCC cases, 73.6% of HBsAg were positive, while those in non-treatment group died within one year. In the treatment group, the average survival time of resection and interventional treatment of HCC were 22.2 and 2.5 months respectively. The majority of non-HCC tumors survived after excision. Conclusion 1 HCC in this group has been significantly more than HB, hepatitis B virus infection is an important reason. 2 HCC resection rate is low, the prognosis is poor, but surgical resection is still the best way to extend the survival of sick children. Surgical resection of non-HCC tumors is much better than HCC.