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目的针对米索前列醇联合缩宫素预防剖宫产术后出血进行观察。方法选取我院2008年9月至2011年9月收治的100例产后出血高危因素的产妇,随机将其分为两组。研究组采用缩宫素+米索前列醇预防产后出血,对照组采用缩宫素。结果研究组术中、术后2、24h出血量明显少于对照组,差异有统计学意义(P<0.05)。研究组平均动脉压、呼吸、脉搏、血氧饱和度、麻醉时间与对照组比较,差异无统计学意义(P>0.05)。结论米索前列醇联合缩宫素能有效减少剖宫产产后出血,加强子宫收缩,且价格低廉、应用安全、方便、简单,无不良反应。
Objective To observe the combination of misoprostol and oxytocin in the prevention of bleeding after cesarean section. Methods Selected 100 cases of postpartum hemorrhage risk women in our hospital from September 2008 to September 2011 were randomly divided into two groups. Study group using oxytocin + misoprostol to prevent postpartum hemorrhage, the control group using oxytocin. Results The bleeding volume of the study group was significantly less than that of the control group at 2 and 24 hours after surgery, the difference was statistically significant (P <0.05). The mean arterial pressure, respiration, pulse rate, oxygen saturation and anesthesia time of the study group were not significantly different from those of the control group (P> 0.05). Conclusion Misoprostol combined with oxytocin can effectively reduce cesarean section postpartum hemorrhage, enhance uterine contractions, and the price is low, the application is safe, convenient, simple and no adverse reactions.