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目的:比较并评价在慢性牙周炎治疗过程中,牙周袋内应用氯己定局部释药系统辅助龈下刮治和根面平整(scaling and root planing,SRP)的临床效果是否优于单纯SRP。方法:主要检索6个数据库,一些全文通过手工检索获得。收集至2009年5月公开发表的中英文牙周局部应用氯己定释药系统辅助龈下刮治和根面平整的随机对照试验,随访时间至少3个月。观察指标为术后牙周探诊深度(probing depth,PD)的减少和临床附着水平(clinical attachment level,CAL)的增加。结果:最终有7个研究纳入本系统评价。Meta分析结果显示,牙周局部应用氯己定释药系统辅助SRP与单纯SRP相比,可以使PD显著降低,而CAL在2个治疗组间无统计学差异。结论:在慢性牙周炎的治疗过程中,牙周局部应用氯己定释药系统辅助SRP可以使牙周探诊深度显著降低。
OBJECTIVE: To compare and evaluate whether the clinical effect of local application of chlorhexidine local release system in subperiosteal scaling and root planing (SRP) during periodontal treatment is better than that of simple SRP. Methods: Six databases were searched, some of them were retrieved by hand. To collect in May 2009 published in Chinese and English periodontal topical application of chlorhexidine release system assisted subgingival scaling and root surface formation of randomized controlled trials, follow-up time of at least 3 months. The observation index was the reduction of postoperative periodontal probing depth (PD) and the increase of clinical attachment level (CAL). Results: Finally, seven studies were included in this review. Meta-analysis showed that periodontal application of chlorhexidine release system assisted SRP compared with simple SRP, can significantly reduce the PD, CAL in the two treatment groups no significant difference. Conclusion: In the treatment of chronic periodontitis, periodontal application of chlorhexidine release system assisted SRP can make a significant reduction in the depth of periodontal exploration.