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传染性单核细胞增多症（IM）是儿童期常见的EB病毒感染所致的传染性疾病，目前尚无理想的治疗方法，且IM治疗不及时可转化为致死性IM，并同一些肿瘤性疾病的发生有关如白血病、淋巴瘤等。1995年1月-1996年1月我们用阿昔洛韦（ACV）治疗IM30例剂量为15mg／kg．d稀释静点，连用7-10天，并与青霉素、病毒唑等一般治疗组对照，结果表明，该药可使患者发热等临床症状快速缓解，肝、脾、淋巴结较早出现缩小、消退，效果明显优于对照组（<0．05），可明显缩短疗程减少住院时间，随访半年无1例发生恶性病转变，通过观察总结，我们认为ACV治疗IM安全有效，是治疗IM值得临床推广的方法。
Infectious mononucleosis (IM) is a common childhood infectious disease caused by Epstein-Barr virus, there is no ideal treatment, and im treatment can not be converted into lethal IM in time, and with some of the tumor The incidence of diseases such as leukemia, lymphoma and so on. January 1995 - January 1996 We treated acyclovir (ACV) with 30 doses of 15 mg / kg. d dilute the static point, once every 7-10 days, and penicillin, ribavirin and other general treatment group control, the results show that the drug can make the patient’s fever and other clinical symptoms quickly relieved, liver, spleen, lymph nodes earlier appeared shrinkage, regression, The effect was significantly better than the control group (<0.05), can significantly shorten the duration of treatment to reduce hospital stay, no follow-up of a case of malignant transformation occurred within six months, through the observation and conclusion, we believe that safe and effective treatment of IM IM is clinically worthy of the promotion of IM method.