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目的:探讨宫颈癌机会性筛查方案的可行性。方法:组织性筛查组:2006年8月在江西靖安县罗湾乡、噪都镇、高湖镇参加子宫颈癌早诊早治项目的已婚妇女3503例。机会性筛查组:2007年9~12月在江西省妇幼保健院参加宫颈癌筛查的1969例门诊患者。通过成本-效果分析比较两组每筛查出一个组织病理阳性病变的平均成本;通过决策树分析考虑机会性筛查可行性。结果:组织性筛查组每筛查出一个组织病理阳性病变平均成本是机会性筛查组的4.94倍(32335元/6552元)。决策树分析提示宫颈癌机会性筛查效益超过成本。结论:实施机会性宫颈癌筛查,可提高宫颈癌及宫颈癌前病变检出率,尤其是癌前病变的检出率。
Objective: To investigate the feasibility of cervical cancer screening program. Methods: Organized screening group: In August 2006, 3503 married women participated in the early diagnosis and treatment of cervical cancer in Luowan Township, Noordu Town and Gahu Township, Jing’an County, Jiangxi Province. Opportunity screening group: 1969 outpatients with cervical cancer screening in Jiangxi MCH from September to December 2007. The cost-effectiveness analysis was used to compare the average cost of screening one histopathological positive lesion in each group and to consider the feasibility of opportunistic screening by decision tree analysis. Results: The average cost of screening one histopathological positive pathological examination group was 4.94 times (32335 yuan / 6552 yuan) in the opportunistic screening group. Decision tree analysis suggests that opportunistic screening of cervical cancer outweighs the cost. Conclusion: The implementation of opportunistic cervical cancer screening can improve the detection rate of cervical cancer and cervical precancerous lesions, especially the detection rate of precancerous lesions.